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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - Nervonic acid

Nervonic acid

CAS No. 506-37-6

Nervonic acid ( cis-15-Tetracosenoic acid;Selacholeic acid )

Catalog No. M19743 CAS No. 506-37-6

Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline sphingosine phosphoric acid and fatty acid.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Nervonic acid
  • Note
    Research use only not for human use.
  • Brief Description
    Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline sphingosine phosphoric acid and fatty acid.
  • Description
    Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline sphingosine phosphoric acid and fatty acid. Nervonic acid may enhance the brain functions and prevent demyelination (Chemical Land21). Research shows that there is negative relationship between nervonic acid and obesity-related risk factors. Demyelination in adrenoleukodystrophy (ALD) is associated with an accumulation of very long chain saturated fatty acids stemming from a genetic defect in the peroxisomal beta oxidation system responsible for the chain shortening of these fatty acids. Sphingolipids from post mortem ALD brain have decreased levels of nervonic acid 24:1(n-9) and increased levels of stearic acid 18:0.
  • Synonyms
    cis-15-Tetracosenoic acid;Selacholeic acid
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    506-37-6
  • Formula Weight
    366.62
  • Molecular Formula
    C24H46O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM;Water:1mg/mL
  • SMILES
    CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Amminger GP et al. Decreased nervonic acid levels in erythrocyte membranes predict psychosis in help-seekingultra-high-risk individuals. Mol Psychiatry. 2012 Dec;17(12):1150-2.
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